Studies and Publications

The study demonstrated that vibration can have anabolic effects (bone formation) when applied to healthy tissues without inflammation, but during orthodontic treatment, in the presence of inflammation, it potentiates catabolic effects (bone resorption) , accelerating tooth movement.

📌 Key findings:

1. HFA increases inflammatory cytokines and osteoclastogenesis , accelerating orthodontic tooth movement.
2. The effect depends on the periodontal ligament (PDL) and only occurs when there are active orthodontic forces.
3. Vibration can be used strategically:
- During treatment, to accelerate movement (catabolic phase).
- After treatment, to increase retention and stability (anabolic phase).
4. There was no evidence of serious adverse effects, suggesting safe and promising clinical use .

The use of vibration significantly accelerated aligner change ( 5.2 days vs. 8.7 days in the control group), resulting in a reduction in total treatment time (135 days vs. 252 days). Furthermore, patients with HFV showed a statistically significant increase in alveolar bone density after treatment, while the control group showed no relevant changes.

The multicenter study, involving 75 patients, demonstrated that the use of the device significantly reduced immediate pain within 5 minutes of aligner changes and also consistently decreased discomfort over 7 days. Adherence was very high (99.6%), with no adverse effects reported.

📌 Key findings:

1. The device provided immediate and prolonged relief from pain associated with orthodontic tooth movement.

2. It was considered viable for use and well-accepted by patients (84% would recommend the device).

3. The short protocol (5 minutes/day) promoted excellent adherence .

4. It can represent an effective alternative to the use of analgesics for pain control during orthodontic treatment.

The study showed that daily vibration improves aligner fit , allows for a reduction in the change interval to as little as 5–7 days without loss of efficiency, increases biological markers of bone remodeling, and decreases pain and discomfort in the first few days after aligner change.

📌 Key findings:
1. Vibration accelerated orthodontic treatment with aligners while maintaining predictability of movement.
2. Patients reported less pain and discomfort .
3. There was an increase in cytokines and bone remodeling factors in the gingival fluid.
4. The short protocol (5 minutes/day) proved to be effective, non-invasive, and clinically relevant .

This pilot study demonstrated that high-frequency acceleration (HFA) at 120 Hz reduced treatment time by up to 66% and also eliminated the need for refinements in the therapy group compared to the controls.

High-frequency vibration facilitated complex dental movements , such as posterior intrusion and incisor decompensation, allowing anterior mandibular rotation and improved facial profile without the need for surgery. Furthermore, an increase in labial bone to the lower incisors was observed after tongue retraction , indicating a protective effect against gingival recessions.

📌 Key findings:
1. The combination of HFV and aligners has allowed for the treatment of complex Class II malocclusion cases without surgery.
2. The treatment was faster (12 ± 6 months) and more predictable.
3. There was a significant improvement in the facial aesthetics and profile of the patients.
4. Vibratory stimulation appeared to induce lip bone formation , reducing future risks of gingival recession.

👉 In summary: High-frequency vibration enhances aligners, accelerates complex movements, and improves bone profile and health in Class II patients without the need for surgery.

High-frequency vibration stimulates the periodontal ligament, increases osteoclastic activity and bone remodeling, resulting in faster tooth movement with a lower risk of root resorption. Studies have shown that its use reduces aligner change time (5–7 days) without compromising treatment predictability, in addition to providing further benefits such as reduced pain, better aligner fit, and greater post-treatment stability.